产品详情
简单介绍:
Recombinant Human C-C motif chemokine 16 protein(CCL16) (Active)
详情介绍:
Chemokine
Recombinant Human C-C motif chemokine 16 protein(CCL16) (Active)
¥620
CCL16
Chemokine CC-4, Chemokine LEC, IL-10-inducible chemokine, LCC-1, Liver-expressed chemokine
Homo sapiens (Human)
Full Length of Mature Protein
9596672; 9545580; 10213461; 9642106; 10235110; 10671294; 15489334
11.2 kDa
Tag-Free
E.Coli
>97% as determined by SDS-PAGE and HPLC.
0.2 μm filtered PBS, pH 7.4 ,lyophilized
Less than 1.0 EU/μg as determined by LAL method.
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
CCL16_HUMAN
Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ
24-120aa
Immunology
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