产品类型:

Chemokine

产品名称:

Recombinant Human Platelet factor 4 protein(PF4) (Active)

uniprot号:

规格:

5μg 20μg 100μg 250μg ￥620

图像:

基因名称:

PF4

别名:

PF-4, Iroplact, Oncostatin-A

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

3098319; 1695112; 11468158; 15815621; 15489334; 893407; 267922; 601757; 6445090; 7644496; 23536183; 8031770; 7547867

分子量:

7.8 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>97% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human fibroblasts is in a concentration of 1.0-10 ng/ml.

Uniprot登录名:

PLF4_HUMAN

参考文献:

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. {ECO:0000269|PubMed:7644496}.

氨基酸序列:

EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES

表达区域:

32-101aa

研究领域:

Immunology