产品类型:

Monoclonal antibodies

产品名称:

WDR77 Monoclonal Antibody

规格:

100μl ￥2383

免疫原:

Purified recombinant human WDR77 protein fragments expressed in E.coli.

宿主:

Mouse

种属反应性:

Human,Mouse,Rat

特异性:

This antibody detects endogenous levels of WDR77 and does not cross-react with related proteins.

应用范围:

ELISA,WB,ICC;Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200

背景:

 Non-catalytic component of the 20S PRMT5-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones.This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.Might play a role in transcription regulation.The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4),methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

克隆类型:

Monoclonal

抗体亚型:

IgG1

纯化方式:

Affinity purified

产品提供形式:

Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

储存条件:

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

别名:

2610312E17Rik; Androgen receptor cofactor p44; C79984; HKMT1069; MEP 50; MEP-50; MEP50; MEP50_HUMAN; Methylosome protein 50; MGC2722; Nbla10071; p44; p44/Mep50; RGD1310479; RP11 552M11.3; WD repeat containing protein 77; WD repeat domain 77;