产品类型:

Monoclonal antibodies

产品名称:

ITGAM Monoclonal Antibody,PE Conjugated

规格:

100μl ￥1600

宿主:

Mouse

种属反应性:

Human

应用范围:

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

背景:

4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.

* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.

This clone is cross reactive with non-human primate.

 

1. Ling NR  et al., eds. (1987) Leucocyte Typing  III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-334

2. Petty HR nd Todd RF. (1996) Immunol. Today 17:209

3. Springer TA (1994) Cell 76:301

4. Stewart M et al (1995) Curr Opin Cell Biol 7:690

克隆类型:

Monoclonal

抗体亚型:

IgG1

产品提供形式:

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

储存条件:

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

克隆号:

4AM216