产品类型:

Monoclonal antibodies

产品名称:

FCGR3A Monoclonal Antibody,PE Conjugated

规格:

100μl ￥1600

宿主:

Mouse

种属反应性:

Human

应用范围:

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

背景:

 COC16 reacts with human CD16, a 50-65 kDa Fcg receptor IIIa (FcgRIII), expressed on NK cells, monocytes/macrophages and granulocytes. It is a human NK cell associated antigen. CD16 is a low affinity receptor for IgG which functions in phagocytosis and ADCC, as well as in signal transduction and NK cell activation. The CD16 antibody blocks the binding of soluble immune complexes to granulocytes.

This clone is cross reactive with non-human primate.

 

1. Knapp, W.,et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.

2. Stroncek, D.F., et al. (1991) Blood 77:1572.

3. Wirthmueller, U., et al.  (1992) J. Exp. Med. 175:1381.

4. Barclay, N.A., et al. (1993) The Leucocyte Antigen FactBook, CD16 section, Academic Press Inc.,San Diego, Calfornia, p. 136.

克隆类型:

Monoclonal

抗体亚型:

IgG1

产品提供形式:

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

储存条件:

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

克隆号:

COC16