KAT8 Monoclonal Antibody

规格:

￥2383

免疫原:

Purified recombinant fragment of human MYST1 expressed in E. Coli

宿主:

Mouse

种属反应性:

Human

特异性:

MYST1 antibody detects endogenous levels of total MYST1

应用范围:

ELISA,WB,IHC,ICC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500,ICC:1:50-1:200

背景:

MYST1 (MYST histone acetyltransferase 1, MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA- and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone

克隆类型:

Monoclonal

纯化方式:

Affinity-chromatography

产品提供形式:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 掳C.Stable for 12 months from date of receipt

储存条件:

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

别名:

EC 2.3.1.48; MYST protein 1; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; hMOF

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