产品类型:

Monoclonal antibodies

产品名称:

PPARGC1A Monoclonal Antibody

规格:

100μl ￥2383

免疫原:

Purified recombinant fragment of human PGC-1alpha expressed in E. Coli

宿主:

Mouse

种属反应性:

Human

特异性:

PGC-1alpha antibody detects endogenous levels of total PGC-1alpha

应用范围:

ELISA,WB;Recommended dilution:WB:1:500-1:5000

背景:

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPAR gamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. 

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克隆类型:

Monoclonal

纯化方式:

Affinity-chromatography

产品提供形式:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 掳C.Stable for 12 months from date of receipt

储存条件:

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

别名:

PPARGC1A; LEM6; PGC1; PGC1A; PGC-1v; PPARGC1; PGC-1(alpha)