产品类型:

Monoclonal antibodies

产品名称:

GRB2 Monoclonal Antibody

规格:

100μl ￥2383

免疫原:

Purified recombinant human GRB2 protein fragments expressed in E.coli.

宿主:

Mouse

种属反应性:

Human,Rat,Mouse,Monkey

特异性:

This antibody detects endogenous levels of GRB2 and does not cross-react with related proteins.

应用范围:

ELISA,WB;Recommended dilution:WB:1:500-1:5000

背景:

 Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.

克隆类型:

Monoclonal

抗体亚型:

IgG1

产品提供形式:

Ascites

储存条件:

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

别名:

Abundant SRC homology; Adapter protein GRB2; ASH; Ash protein; EGFRBP GRB2; Epidermal growth factor receptor binding protein; Epidermal growth factor receptor binding protein GRB2; GRB 2; GRB2 adapter protein; Grb2; GRB2_HUMAN; Grb3 3;