产品详情
简单介绍：
Complement Component 3c (C3c)
详情介绍：
| Product Name | Complement Component 3c |
| Source | Human Plasma |
| Catalogue Number | 194-31 |
| Purity | > 95% (SDS-PAGE) |
| Form | Liquid |
| Protein | 0.5 - 5.0 mg/mL (A280 E0.1% = 1.03) |
| Formulation | 0.2 micron filtered frozen solution in phosphate buffered saline, pH 7.4. |
| Related Products | anti-Human Complement C3 (C3) Polyclonal Antibody Complement C3c (C3c) Antigen - Lyophilized |
| Storage | -20°C |
| Recertification | 2 years |
| Product Details | Complement C3 is synthesized as a single chain of 185 kDa and is processed in the plasma to a disulfide-linked heterodimer consisting of an α-chain (115 kDa) and a β-chain (70 kDa). During complement activation, C3 is cleaved by C3 convertases to C3a (9 kDa) and C3b (176 kDa) comprised of the large C-terminal portion of the α-chain and the β-chain. Factor I further cleaves C3b into C3c (140 kDa), C3d (35 kDa), and C3g (7 kDa). The current protocol yields C3c, however intact C3 and/or C3a/C3b may be co-purified. |
| Molecular Weight | 138,000 |
| Synonyms | C3c |
| Gene | C3 |
| Gene ID | 718 |
| Gene Synonyms | AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1 |
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