- Product Code: PDF-4415-s
- Synonyms/Product Alternate Names: Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg, HD-5, Human Defensin-5, alpha-Defensin-5, DEFA5
- Antimicrobial Peptide in Paneth Cells
- Storage Conditions: -20 °C
- Molecular Weight: 3582.1
- Molecular Formula: C144H238N50O45S6
- Disulfide Bonds: (Disulfide bonds between Cys3-Cys31, Cys5-Cys20, and Cys10-Cys30)
- One-Letter Code:H-ATCYCRTGRCATRESLSGVCEISGRLYRLCCR-OH
T. Ganz, M.E. Selsted, D. Szklarek, S.S.L. Harwig, K. Daher, D.F. Bainton, and R.I. Lehrer, J. Clin. Invest., 76, 1427 (1985). (Original; Isolation of HNP 1-3)
M.E. Selsted, S.S.L. Harwig, T. Ganz, J.W. Schilling, and R.I. Lehrer, J. Clin. Invest., 76, 1436 (1985). (Original; Structure of HNP 1-3)
X.-M. Fang, Q. Shu, Q.-X. Chen, M. Book, H.-G. Sahl, A. Hoeft, and F. Stuber, Eur. J. Clin. Invest., 33, 82 (2003). (Histochem.; Regulation of Expression)
R.I. Lehrer and T. Ganz, Ann. N.Y. Acad. Sci., 797, 228 (1996). (Review)
E. Martin Porter, M.A. Poles, J.S. Lee, J. Naitoh, C.L. Bevins, amd T. Ganz, FEBS Lett., 434, 272 (1998). (Endogenous Form)
N.H. Salzman, D. Ghosh, K.M. Huttner, Y. Paterson, and C.L. Bevins, Nature, 422, 522 (2003). (Pharmacol.)
P. Kelly, R. Feakins, P. Domizio, J. Murphy, C. Bevins, J. Wilson, G. Mcphail, R. Poulsom, and W. Dhaliwal, Clin. Exp. Immunol., 135, 303 (2004). (Histochem.; Location in AIDS Patients)
F.T. Lundy, D.F. Orr, J.R. Gallagher, P. Maxwell, C. Shaw, S.S. Napier, C.G. Cowan, P.-J. Lamey, and J.J. Marley, Oral Oncol., 40, 139 (2004). (Pharmacol.; Role in Tumor Invasion)
L. Zhang, W. Yu, T. He, J. Yu, R.E. Caffrey, E.A. Dalmasso, S. Fu, T. Pham, J. Mei, J.J. Ho, W. Zhang, P. Lopez, and D.D. Ho, Science, 298, 995 (2002)(Pharmacol.; Anti-HIV-1 Activity)
R.N. Cunliffe, Mol. Immunol., 40, 463 (2003). (Histochem.; a-Defensin in Gastrointestinal Tract) D.E. Jones and C.L. Bevins, J. Biol. Chem., 267, 23216 (1992). (Original)
