产品详情
简单介绍：
PyBOP®
详情介绍：
- Product Code: KPC-1068-PI
- Synonyms/Product Alternate Names: Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
- Analogue of the BOP coupling reagent which does not form carcinogenic HMPA as by-product. Coupling reactions are rapid, being nearly complete within a few minutes. May be used in place of BOP in peptide synthesis without loss of coupling efficiency. Especially useful for cyclization steps for the activation of hindered amino acid.
- Storage Conditions: 2~10° C
- Purity: ≥99.0%
- Molecular Weight: 520.39
- Molecular Formula: C18H28N6OPPF6
- CAS Number: [128625-52-5]
J. Putura, P.M. Turunen, M.H. Jäntti, M.E. Ekholm, and J.P. Kukkonen, Neurosci. Lett., 494, 57 (2011). (Pharmacol.)
J. Coste, D. Le-Nguyen, B. Castro, PyBOP®: A new peptide coupling reagent devoid of toxic by-product
S. Asahi, S.-I. Egashira, M. Matsuda, H. Iwaasa, A. Kanatani, M. Ohkubo, M. Ihara, and H. Morishima, Bioorg. Med. Chem. Lett., 13, 111 (2003). (Original; Structure-Activity Relationship & Pharmacol.)
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