产品详情
简单介绍：
Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO
21050
详情介绍：
Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 21050 | 1.5 mL | 55.00$ | in stock |
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Copper (II)-TBTA complex is a component of catalyst used for Click Chemistry conjugation reaction. Actual catalyst contains Cu(I), but this reagent cannot be stored, and should be generated from Copper(II)-TBTA complex in situ by reduction. To activate this catalyst, reductant such as ascorbic acid should be added to reaction mixture.
Recommended protocol
Click-Chemistry Labeling of Oligonucleotides and DNA
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| Appearance: | blue solution |
| Molecular weight: | 690.23 |
| Molecular formula: | C30H30CuN10O4S |
| Quality control: | functional testing (Click Chemistry) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. |
| MSDS: | Download |
Product citations
- Routh, A.; Ji, P.; Jaworski, E.; Xia, Z.; Li, W.; Wagner, E.J. Poly(A)-ClickSeq: click-chemistry for next-generation 3′-end sequencing without RNA enrichment or fragmentation. Nucleic Acids Research, 2017, 45(12), e112. doi: 10.1093/nar/gkx286
- Jaworski, E.; Routh, A. Parallel ClickSeq and Nanopore sequencing elucidates the rapid evolution of defective-interfering RNAs in Flock House virus. PLOS Pathogens, 2017, 13(5), e1006365. doi: 10.1371/journal.ppat.1006365
- Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
- Taskova, M.; Madsen, C.S.; Jensen, K.J.; Hansen, L.H.; Vester, B.; Astakhova, K. Antisense oligonucleotides internally labeled with peptides show improved target recognition and stability to enzymatic degradation. Bioconjugate Chemistry, 2017, 28(3), 768–774. doi: 10.1021/acs.bioconjchem.6b00567
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