产品详情
简单介绍：
Azidobutyric acid NHS ester
33720 43720 53720 63720
详情介绍：
Azidobutyric acid NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 33720 | 10 mg | 60.00$ | in stock | |
| 43720 | 25 mg | 95.00$ | in stock | |
| 53720 | 50 mg | 185.00$ | in stock | |
| 63720 | 100 mg | 290.00$ | in stock |
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Convert your proteins and peptides into Click Chemistry reactive form with this reagent.
While Click Chemistry involves reaction between terminal alkyne and azide, both azides and alkynes are very uncommon in nature. However, there are reagents to attach these fragments to abundant amino groups which are ubiquitous in the world of biomolecules. This azido-NHS ester is designed for the conversion of proteins, peptides, amino-DNA, and other amines into Click Chemistry reactive azides.
Recommended protocol
NHS ester labeling of amino biomolecules
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Cyanine3 amine
Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.Alkyne hydrazide
Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.Alkyne maleimide
Maleimide reagent for the attachment of alkyne functional group to proteins, peptides, and other molecules bearing SH (thiol) groups, including cysteine residues.General properties
| Appearance: | colorless solid |
| Mass spec M+ increment: | 111.0 |
| Molecular weight: | 226.19 |
| Molecular formula: | C8H10N4O4 |
| Solubility: | soluble in organic solvents (DMF, DMSO) |
| Quality control: | NMR 1H (95%), HPLC |
| Storage conditions: | Storage: 12 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
Product citations
- Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
- Bu, J.; Pilo, A.L.; McLuckey, S.A. Gas Phase Click Chemistry via Ion/Ion Reactions. International Journal of Mass Spectrometry, 2015, 390, 118–123. doi: 10.1016/j.ijms.2015.05.010
- Potapova, I.; Eglin, D.; Laschke, M.W.; Bischoff, M.; Richards, R.G.; Moriarty, T.F. Two-step labeling of Staphylococcus aureus with Lysostaphin-Azide and DIBO-Alexa using click chemistry. Journal of Microbiological Methods, 2013, 92(1), 90-98. doi:10.1016/j.mimet.2012.11.004
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