产品详情
简单介绍：
NKG2D
详情介绍：
PURE - anti Human CD326 (EpCAM) -
| Reference | Size | Price | Quantity | Add to cart |
|---|---|---|---|---|
| 326PU-01MG | 100 test |
190,00 € tax excl.
|
|
Product Description
- IgG1
- FCM
- PURE
- Human small cell lung carcinoma cell line NCl-H69
- Human
- The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
- RUO
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The 1D11 monoclonal antibody reacts with the human NKG2D, a 42 kDa lectin-like molecule expressed by NK cells, gamma delta T cells, CD8+ T cells, and some CD4+ T cells. Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors. The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma. 5C6 and 1D11 block binding of soluble MICA to gamma delta TCR T cell clones and inhibit lysis by these cells. 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells.
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