产品详情
简单介绍:
Biotin - anti human CD326 (EpCAM) - Clone VU-1D9
详情介绍:
Biotin - anti Human CD326 (EpCAM) - VU-1D9
Reference | Size | Price | Quantity | Add to cart |
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326B-01MG | 100 test |
180,00 € tax excl.
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Product Description
- VU-1D9
- IgG1
- Biotin
- Please refer to the Certificate of Analysis for the lot-specific concentration.
- Human small cell lung carcinoma cell line NCl-H69
- Human
- The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
- RUO
- CD314, clone1D11, is a mAb intended for the identification of NK cells, gamma delta T cells, CD8+ T cells, and some CD4+ T cells. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
- Store in the dark at 2-8 °C
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The 1D11 monoclonal antibody reacts with the human NKG2D, a 42 kDa lectin-like molecule expressed by NK cells, gamma delta T cells, CD8+ T cells, and some CD4+ T cells. Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors. The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma. 5C6 and 1D11 block binding of soluble MICA to gamma delta TCR T cell clones and inhibit lysis by these cells. 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells.
- NKG2D
- 40 kDa
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