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  • 产品名称:CD4 - IMMUNOSTEP. WE KNOW HOW

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简单介绍:
CD4 - IMMUNOSTEP. WE KNOW HOW
详情介绍:

PerCP - anti Human CD4 - HP2/6

Reference Size Price Quantity Add to cart
4PP1-100T 100 test
253,00 € tax excl.

Product Description

  • HP2/6
  • FCM
  • PerCP
  • T cells from leukemic HPB-ALL
  • Human
  • PBS, 0,09% sodium Azide, may contain carrier protein-stabilizer
  • IVD-CE
CD4 View larger

Reactivity: The monoclonal antibody is directed against the CD4-antigen (T4-antigen),which is?expressed on human peripheral T lymphocytes and 80% of thymocytes. The monoclonal antibody reacts?on a low level with human monocytes and macrophages. The monoclonal antibody does not react with?B-cells, granulocytes and thrombocytes.

Specificity: 60Kd MW lymphocyte surface antigen identified by monoclonal antibodies belonging to the?CD4 cluster and present on 54% of peripheral blood T lymphocytes, 50% of thymocytes and some?malignant cells of T cell origin. Normal B lymphocytes, monocytes or granulocytes do not express?surface CD4 antigen although cytoplasmic expression has been observed in monocytes/macrophages.?The CD4 positive T lymphocyte subpopulation has been characterised functionally as comprising helper?cells active in amplification of immune responses.

Publication references:?

  • Acebes-Huerta A. et al. Lenalidomide Induces Immunomodulation in Chronic Lymphocytic Leukemia and Enhances Antitumor Immune Responses Mediated by NK and CD4 T Cells. 2014 Biomed Res Int.?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182694/
  • Huergo-Zapico L et al. Expansion of NK Cells and Reduction of NKG2D Expression in Chronic Lymphocytic Leukemia. Correlation with Progressive Disease. 2014 PLoS One
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186792/
  • T4, L3T4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-7
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