产品详情
简单介绍：
Anti-NUMB Antibody
详情介绍：
Overview
| Name: | Anti-NUMB Antibody See all NUMB primary antibodies
|
| Description: | Goat polyclonal antibody to NUMB. |
| Applications: | ELISA, WB, ICC, IP |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide corresponding to Human NUMB (C terminal). |
| Sequence: | C-PFSSDLQKTFEIEL |
| Host: | Goat |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 100 µg at 0.5 mg/ml. |
| Product Form: | Liquid |
| Formulation: | Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage (By similarity). |
| Post-Translational Modification: | Phosphorylated on Ser-275 and Ser-294 by CaMK1. |
| Cellular Location: | Membrane. |
| Database Links: |
|
| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
相关文章
