产品详情
简单介绍：
Anti-ENC-1 Antibody
详情介绍：
Overview
| Name: | Anti-ENC-1 Antibody See all ENC-1 primary antibodies
|
| Description: | Chicken polyclonal antibody to ENC-1 |
| Applications: | E, WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Raised against a 13 amino acid peptide near the center of human ENC-1. |
| Host: | Chicken |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Affinity chromatography purified via peptide column |
| Formulation: | Supplied in PBS containing 0.02% sodium azide. |
| Storage: | Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Target
| Function: | Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin-mediated proteasomal degradation mechanism (By similarity). |
| Tissue Specificity: | Primarily expressed in the nervous system. |
| Post-Translational Modification: | Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. Quinone-induced oxidative stress increases its ubiquitination (By similarity). |
| Cellular Location: | Nucleus matrix. Cytoplasm. Cytoplasm > Cytoskeleton. Interacts with the actin cytoskeleton. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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