产品详情
简单介绍：
Anti-Ephrin-B1 / 2 Antibody
详情介绍：
Overview
| Name: | Anti-Ephrin-B1 / 2 Antibody See all Ephrin-B1 primary antibodies
|
| Description: | Rabbit polyclonal antibody to Ephrin-B1 / 2 |
| Specificity: | Ephrin-B1 / 2 Polyclonal Antibody detects endogenous levels of Ephrin-B1 / 2 protein. |
| Applications: | WB, IHC, ELISA |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human Ephrin-B1 / 2 around the non-phosphorylation site of Y330. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1mg / ml |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage: | Store at -20?C / 1 year |
Target
| Function: | Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). |
| Tissue Specificity: | Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas. |
| Involvement in Disease: | Craniofrontonasal syndrome: X-linked inherited syndrome characterized by hypertelorism, coronal synostosis with brachycephaly, downslanting palpebral fissures, clefting of the nasal tip, joint anomalies, longitudinally grooved fingernails and other digital anomalies. |
| Sequence Similarities: | Belongs to the ephrin family. |
| Post-Translational Modification: | Inducible phosphorylation of tyrosine residues in the cytoplasmic domain. |
| Cellular Location: | Membrane. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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