产品详情
简单介绍:
Anti-EPO Antibody
详情介绍:
Overview
Name: | Anti-EPO Antibody See all EPO primary antibodies
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Description: | Mouse monoclonal (85) antibody to Erythropoietin. |
Specificity: | This antibody specifically recognises human EPO. |
Applications: | ELISA, WB |
Reactivity: | Human |
Cross Reactivity: | This antibody does not recognise IL-8, IL-16, IL-7, MCP-1, TNF-β, GM-CSF, M-CSF, IL-1β, bFGF, human serum albumin and bovine serum albumin. |
Immunogen: | Purified CHO cell-expressed recombinant human EPO. |
Host: | Mouse |
Clonality: | Monoclonal |
Clone: | 85 |
Myeloma: | Sp2/0-Ag14 |
Isotype: | IgG1 |
Conjugate: | Unconjugated |
Concentration: | Reconstitution dependent. |
Purity: | Protein G affinity chromatagraphy. |
Product Form: | Lyophilised |
Reconstitution: | Reconstitute with double distilled water. |
Formulation: | Lyophilised from a solution of 0.01M Phosphate Buffered Saline, pH 7.2. |
Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
Function: | Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. |
Tissue Specificity: | Produced by kidney or liver of ***** mammals and by liver of fetal or neonatal mammals. |
Involvement in Disease: | Microvascular complications of diabetes 2: Pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic *****s. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. |
Sequence Similarities: | Belongs to the EPO/TPO family. |
Cellular Location: | Secreted. |
Database Links: |
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Synonyms: | |
Information: | Target information shown above is from the UniProt Consortium. |
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