产品类型:

Interleukin

产品名称:

Recombinant Mouse Interleukin-1 receptor antagonist protein(Il1rn) (Active)

uniprot号:

规格:

20μg 100μg 250μg ￥620

图像:

基因名称:

Il1rn

别名:

IL-1RN, IRAP, IL1 inhibitor

种属:

Mus musculus (Mouse)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

1828262; 1830498; 8003626; 9550387; 1828896; 1834470

分子量:

17.3 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>97% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1α- dependent proliferation of murine D10S cells is less than 50 ng/ml, corresponding to a specific activity of >2.0x10⁴ IU/mg in the presence of 50 pg/ml rHuIL-1α.

Uniprot登录名:

IL1RA_MOUSE

参考文献:

Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.

氨基酸序列:

RPSGKRPCKM QAFRIWDTNQ KTFYLRNNQL IAGYLQGPNI KLEEKIDMVP IDLHSVFLGI HGGKLCLSCA KSGDDIKLQL EEVNITDLSK NKEEDKRFTF IRSEKGPTTS FESAACPGWF LCTTLEADRP VSLTNTPEEP LIVTKFYFQE DQ

表达区域:

27-178aa

研究领域:

Immunology