产品类型:

Hormone

产品名称:

Recombinant Human Leptin protein(LEP) (Active)

uniprot号:

规格:

200μg 1000μg ￥620

图像:

基因名称:

LEP

别名:

Obese protein

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

7984236; 7789654; 8626726; 7499240; 8621021; 15489334; 10428856; 9166907; 9144295; 9500540

分子量:

16.0 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>97% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human Leptin R transfected BaF3 murine proB cells is less than 2 ng/ml, corresponding to a specific activity of >5.0x10⁵ IU/mg.

Uniprot登录名:

LEP_HUMAN

参考文献:

May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.

氨基酸序列:

VPIQKVQDDT KTLIKTIVTR INDISHTQSV SSKQKVTGLD FIPGLHPILT LSKMDQTLAV YQQILTSMPS RNVIQISNDL ENLRDLLHVL AFSKSCHLPW ASGLETLDSL GGVLEASGYS TEVVALSRLQ GSLQDMLWQL DLSPGC

表达区域:

22-167aa

研究领域:

Signal Transduction