产品详情
简单介绍:
Recombinant Human C-C motif chemokine 21 protein(CCL21) (Active)
详情介绍:
Chemokine
Recombinant Human C-C motif chemokine 21 protein(CCL21) (Active)
¥620
CCL21
6Ckine, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21
Homo sapiens (Human)
Full Length of Mature Protein
9235955; 9257816; 9300671; 9419363; 12975309; 15489334; 9507024; 23341447; 22221265
12.2 kDa
Tag-Free
E.Coli
>97% as determined by SDS-PAGE and HPLC.
0.2 μm filtered PBS, pH 7.4 ,lyophilized
Less than 1.0 EU/μg as determined by LAL method.
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 10-100 ng/ml.
CCL21_HUMAN
Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P
24-134aa
Immunology
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