产品类型:

Chemokine

产品名称:

Recombinant Mouse C-C motif chemokine 5 protein(Ccl5) (Active)

uniprot号:

规格:

5μg 20μg 100μg 250μg ￥620

图像:

基因名称:

Ccl5

别名:

MuRantes, Small-inducible cytokine A5, T-cell-specific protein RANTES

种属:

Mus musculus (Mouse)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

1375672; 1376260; 7507961; 7513046; 10438970; 16141072; 15489334

分子量:

7.9 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>97% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T lymphocytes is in a concentration range of 1.0-10 ng/ml.

Uniprot登录名:

CCL5_MOUSE

参考文献:

Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. {ECO:0000250|UniProtKB:P13501}.

氨基酸序列:

SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS

表达区域:

24-91aa

研究领域:

Immunology