产品详情
简单介绍:
Recombinant Rat C-C motif chemokine 3 protein(Ccl3) (Active)
详情介绍:
Chemokine
Recombinant Rat C-C motif chemokine 3 protein(Ccl3) (Active)
¥620
Ccl3
Macrophage inflammatory protein 1-alpha, Small-inducible cytokine A3
Rattus norvegicus (Rat)
Full Length of Mature Protein
7779098; 7722328; 17218081; 8607872
7.9 kDa
Tag-Free
E.Coli
>98% as determined by SDS-PAGE and HPLC.
0.2 μm filtered PBS, pH 7.4 ,lyophilized
Less than 1.0 EU/μg as determined by LAL method.
Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using human blood monocytes is in a concentration range of 10-100 ng/ml.
CCL3_RAT
Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.
APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA
24-92aa
Immunology
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