产品类型:

Interleukin

产品名称:

Recombinant Mouse Interleukin-1 beta protein(Il1b) (Active)

uniprot号:

规格:

2μg 10μg 100μg 250μg ￥620

图像:

基因名称:

Il1b

别名:

IL-1 beta

种属:

Mus musculus (Mouse)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

3491144; 3492706; 15489334; 2967326; 1807351

分子量:

17.5 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>96% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 2 pg/ml, corresponding to a specific activity of >5.0x10⁸ IU/mg.

Uniprot登录名:

IL1B_MOUSE

参考文献:

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

氨基酸序列:

VPIRQLHYRL RDEQQKSLVL SDPYELKALH LNGQNINQQV IFSMSFVQGE PSNDKIPVAL GLKGKNLYLS CVMKDGTPTL QLESVDPKQY PKKKMEKRFV FNKIEVKSKV EFESAEFPNW YISTSQAEHK PVFLGNNSGQ DIIDFTMESV SS

表达区域:

118-269aa

研究领域:

Immunology