产品类型:

Interleukin

产品名称:

Recombinant Human Interleukin-1 alpha protein(IL1A) (Active)

uniprot号:

规格:

2μg 10μg 100μg 250μg ￥620

图像:

基因名称:

IL1A

别名:

IL-1 alpha

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

2989698; 3486405; 2994016; 2635664; 3485152; 3493774; 11991722; 14702039; 15815621; 15489334; 3281727; 8346241; 2346741

分子量:

18.0 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>97% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 1.0 pg/ml, corresponding to a specific activity of >1.0x10⁹ IU/mg.

Uniprot登录名:

IL1A_HUMAN

参考文献:

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

氨基酸序列:

SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA

表达区域:

113-271aa

研究领域:

Immunology