产品类型:

Chemokine

产品名称:

Recombinant Human C-X-C motif chemokine 6 protein(CXCL6) (Active)

uniprot号:

规格:

5μg 20μg 100μg 250μg ￥620

图像:

基因名称:

CXCL6

别名:

Chemokine alpha 3, Granulocyte chemotactic protein 2, GCP-2, Small-inducible cytokine B6

种属:

Homo sapiens (Human)

蛋白描述:

Partial

PubMed ID:

9164944; 14702039; 15815621; 15489334; 9057843; 8399143; 8423327; 18443119

分子量:

7.9 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>98% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 10-50 ng/ml.

Uniprot登录名:

CXCL6_HUMAN

参考文献:

Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). {ECO:0000269|PubMed:18443119, ECO:0000269|PubMed:8399143, ECO:0000269|PubMed:8423327, ECO:0000269|PubMed:9057843}.

氨基酸序列:

VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN

表达区域:

43-114aa

研究领域:

Immunology