产品类型:

Monoclonal antibodies

产品名称:

TNFRSF10B Monoclonal Antibody

规格:

100μl ￥2383

免疫原:

Purified recombinant human TNFRSF10B protein fragments expressed in E.coli.

宿主:

Mouse

种属反应性:

Human,Mouse

特异性:

This antibody detects endogenous levels of TNFRSF10B and does not cross-react with related proteins.

应用范围:

ELISA,WB,ICC;Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200

背景:

 Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor.The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.Essential for ER stress-induced apoptosis.

克隆类型:

Monoclonal

抗体亚型:

IgG1

纯化方式:

Affinity purified

产品提供形式:

Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.

储存条件:

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

别名:

Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L;