产品类型:

Monoclonal antibodies

产品名称:

CD4 Monoclonal Antibody,Purified

规格:

100μl ￥1600

宿主:

Mouse

种属反应性:

Human

应用范围:

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

背景:

 CD4, also known as T4, is a 55 kD single chain transmembrane glycoprotein and belongs to immunoglobulin superfamily. CD4 is found on most thymocytes, a subset of T cells and at low level on monocytes/macrophages.

CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molecules) and HIV infection (CD4 is primary receptor for HIV-1 surface glycoprotein gp120). CD4 regulates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction.

 

1. Ledbetter, J et al. (1981) J Exp Med  153:310-323.

2. Haynes , B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.

3. Clevers H et al. (1988). Ann Rev Immunol 6 : 629-662.

4. Barclay, N et al. (1993). The Leucocyte Factsbook. Academic Press. San Diego.

克隆类型:

Monoclonal

抗体亚型:

Mouse IgG2b

产品提供形式:

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide

储存条件:

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

克隆号:

4AT4