产品详情
简单介绍:
Complement Component 4c (C4c)
详情介绍:
Product Name | Complement Component 4c |
Source | Human Plasma |
Catalogue Number | 194-41 |
Purity | > 95% (SDS-PAGE) |
Form | Liquid |
Protein | 1 - 5 mg/mL (E0.1%280nm = 0.92) |
Identity | Confirmed by Western Blot |
Formulation | 0.2 micron filtered frozen solution in phosphate buffered saline, pH 7.4. |
Related Products | anti-Human Complement C4 (C4) Polyclonal Antibody Complement C4c (C4c) Antigen - Lyophilized |
Recertification | 1 year |
Storage | -20°C |
Product Details | Complement C4 (200 kDa) is composed of three polypeptide chains – α (93 kDa), β (78 kDa), and γ (33 kDa). During complement activation, C4 is cleaved by the serine protease C1s to C4a (9 kDa) and C4b (190 kDa). C4b is further cleaved by factor I to C4d (45 kDa) and C4c (140 kDa). The current protocol yields C4c, however intact C4 and/or C4b and C4d may be co-purified. |
Synonyms | C4, Complement C4, C4c |
Gene | C4A, C4B |
Gene Synonyms | DAMC-258G8.6, C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, DADB-112B14.11-001, C4B1, C4B12, C4B2, C4B3, C4B5, C4BD, C4B_2, C4F, CH, CO4, CPAMD3 |
Gene ID | 720, 721 |
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