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Fluidigm(富鲁达)高通量基因分析系统相关应用技术文章
Fluidigm(富鲁达)高通量基因分析系统相关应用技术文章
Research Publications Featuring Fluidigm Products
2010
Panula, S., Medrano, J.V., Kee, K., Bergström,R.,Nguyen, H.N., Byers, B., Wilson, K.D., Wu, J.C., Simon,C.,Hovatta, O., and Reijo Pera, R.A. December 23, 2011. Human germ cell differentiation from fetal- and*****-derived induced pluripotent stem cells.
HumanMolecular Genetics
Moltzahn, F., Olshen, A.B., Baehner, L., Peek, A.S., Fong,L.,Stoppler, H.J., Simko, J., Hilton, J.F., Carroll, P.R.,andBlelloch, R. November 22, 2010. Microfluidic based multiplex qRT-PCR identifies diagnostic andprognostic microRNA signatures in sera of prostate cancerpatients.
Cancer Research
Blainey, P., and Quake, S. November 11, 2010. Digital MDA for enumeration of total nucleic acidcontamination.
Nucleic Acid Research
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Kocarnick, J.D., Hutter, C.M., Slattery, M.L., Berndt,S.I.,Hsu, L., Duggan, D.J., Muehling, J., Caan, B.J., Beresford,S.A.A.,Rajkovic, A., Sarto, G.E., Marshall, J.R., Hammad, N.,Wallace,R.B., Makar, K.W., Prentice, R.L., Potter, J.D., Hayes,R.B., andPeters, U. October 26, 2010. Characterization of9p24 Risk Locus and Colorectal Adenomaand Cancer: Gene-EnvironmentInteraction and Meta-Analysis.
Cancer Epidemiology,Biomarkers & Prevention
Wong, C.C., Loewke, K.E., Bossert, N.L., Behr, B., DeJonge,C.J., Baer T.M., & Reijo Pera, R.A. October 3, 2010.Non-invasiveimaging of human embryos before embryonic genome activationpredicts development to the blastocyst stage.
NatureBiotechnology
Menzel, S., Qin, J., Vasavda, N., Thein, S.L., Ramakrishnan,R.September 24, 2010. Experimental Generation of SNP Haplotype Signatures in Patientswith Sickle Cell Anaemia.
PLoS One
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Baak-Pablo, R., Dezentje, V., Guchelaar, H., & vanderStraaten, T. September 16, 2010. Genotyping of DNA Samples Isolated from Formalin-FixedParaffin-Embedded Tissues Using Preamplification.
Journalof Molecular Diagnostics
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Tehranchi, R., Woll, P.S., Anderson, K., et al. September9,2010. PersistentMalignant Stem Cells in del(5q)Myelodysplasia in Remission.
The New England Journal ofMedicine
Voelkerding, K.V., Dames, S., and Durtschi, J.D. September5,2010. Next Generation Sequencing for Clinical Diagnostics-Principles andApplication to Targeted Resequencing for HypertrophicCardiomyopathy.
Journal of Molecular Diagnostics
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Nakamura, Y., Arai, F., Iwasaki, H., Hosokawa, K.,Kobayashi,I., Gomei, Y., Matsumoto, Y., Yoshihara, H., Suda, T.September 2,2010. Isolation and characterization of endosteal niche cell populationsthat regulate hematopoietic stem cells.
Blood
.
Pander, J., Wessels, J. A. M., Gelderblom, H., van derStraaten,T., Punt, C.J.A. & Guchelaar, H.-J. August 17, 2010Pharmacogenetic interaction analysis for the efficacy of systemictreatment in metastatic colorectal cancer.
Annals ofOncology
Petriv, O.I., Kuchenbauer, F., Delaney, A.D., et al. August11,2010. Comprehensive microRNA expression profiling of the hematopoietichierarchy.
PNAS
Blauw, H.M., Al-Chalabi, A., Andersen, P.M., et al. August10,2010. A large genome scan for rare CNVs in amyotrophic lateralsclerosis.
Human Molecular Genetics
Hahn, S., Jackson, L.G., and Zimmermann, B.G. August 5,2010.Prenataldiagnosis of fetal aneuploidies: post-genomic developments.
Genome Medicine
Schoeffler, A.J., May, A.P. and Berger, J.M. July 31,2010.A domain insertion in Escherichia coli GyrB adopts a novel foldthat plays a critical role in gyrase function.
NucleaicAcids Research
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Hosokawa, K., Arai, F., Yoshihara, H., Iwasaki, H.,Nakamura,Y., Gomei, Y. and Suda, T. July 29, 2010. Knockdown of N-cadherin suppresses the long-term engraftment ofhematopoietic stem cells.
BLOOD
Iwasaki, H., Arai, F., Kubota, Y., Dahl, M. and Suda, T.July29, 2010. Endothelial protein C receptor-expressing hematopoietic stem cellsreside in the perisinusoidal niche in fetal liver.
BLOOD
Hennessy, B.T.J., Timms, K.M., Carey, M.S., et al. July 6,2010.Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number ofPatients That Benefit From Poly (ADP Ribose) Polymerase Inhibitorsin Ovarian Cancer.
Journal of Clinical Oncology
Chaussabel, D., Pascual, V. and Banchereau, J. July1,2010. Assessing the humanimmune system through blood transcriptomics.
BMCBiology
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Tay, S., Hughey, J.J., Lee, T.K., Lipniacki, T., Quake, S.R.andCovert, M.W. June 27, 2010. Single-cell NF-kB dynamics reveal digital activation and analogueinformation processing.
Nature
Kee, K., Flores, M., Cedars, M.I. and Pera, R. A .R. June18,2010. Human Primordial Germ Cell Formation Is Diminished by Exposure toEnvironmental Toxicants Acting through the AHR SignalingPathway.
Toxicological Sciences
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Fan, C., Blumenfeld, Y.J., Chitkara, U., Hudgins, L., andQuake,S.R. June 17, 2010. Analysis of the Size Distributions of Fetal and Maternal Cell-FreeDNA by Paired-End Sequencing.
Clinical Chemistry
Hahn, S. and Zimmermann, B.G. June 17, 2010. Cell-Free DNA in Maternal Plasma: Has the Size-Distribution PuzzleBeen Solved?
Clinical Chemistry
Hart, C.P. June 15, 2010. Product Focus:High-Content Screening and Imaging:Instrumentation, Analysis, andApplications.
Journal ofBiomolecular Sceening
McElroy, S.L., Byrne, J.A., Chavez,S.L., Behr,B., Hsueh, A.J.,Westphal, L.M., ReijoPera, R.A. June 7,2010. Parthenogenic Blastocysts Derived from Cumulus-Free In VitroMatured Human Oocytes.
PLoS ONE
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Cole, B.B., Smith, R.W., Jenkins, K.M., Graham, B.B.,Reynolds,P.R. and Reynolds, S.D. June 3, 2010. Tracheal Basal Cells: A Facultative Progenitor Cell Pool.
American Journal of Pathology
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Paez, D., Pare, L., Espinosa, I., Salazar, J., Del Rio,E.,Barnadas, A., Marcuello, E. and Baiget, M. May 18, 2010.Immunoglobulin G fragment C receptor polymorphisms and KRASmutations: Are they useful biomarkers of clinical outcome inadvanced colorectal cancer treated with anti-EGFR-basedtherapy?
Cancer Science [Epub ahead of print]
Freedman, J.E., Larson, M.G., Tanriverdi, K., O'Donnell,C.J.,Morin, K., Hakanson, A.S., Vasan, R.S., Johnson, A.D.,Iafrati,M.D., and Benjamin E.J. May 14, 2010. Relation of Platelet and Leukocyte Inflammatory Transcripts to BodyMass Index in the Framingham Heart Study.
A.H.A.Circulation
Spitali, P., Heemskerk, H., Vossen, R.H., Ferlini, A.,denDunnen, J.T., AC 't Hoen, P. and Aartsma-Rus, A. May 10,2010.Accurate quantification of dystrophin mRNA and exon skipping levelsin Duchenne Muscular Dystrophy.
LaboratoryInvestigation
Sagreiya, H., Berube, C,. Wen, A., Ramakrishnan, R., Mir,A.,Hamilton, A., Altman, R.B. May 3, 2010. Extending and evaluating a warfarin dosing algorithm that includesCYP4F2 and pooled rare variants of CYP2C9.
Pharmacogeneticsand Genomics
Burns, M.J., Burrell, A.M., and Foy, C.A. April 30, 2010.Theapplicability of digital PCR for the assessment of detectionlimitsin GMO analysis.
Woyke, T., Tighe, D., Mavromatis, K., Clum, A., Copeland,A.,Schackwitz, W., Lapidus, A., Wu, D., McCutcheon, J.P.,McDonald,B.R., Moran, N.A., Bristow, J., Cheng, J. April 23, 2010.One Bacterial Cell, One Complete Genome
PLoS ONE
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Guo, G., Huss, M., Tong, G.Q., Wang, C., Sun, L., Clarke,N.D.,and Robson, P. April 20, 2010. Resolution of Cell Fate Decisions Revealed by Single-Cell GeneExpression Analysis from Zygote to Blastocyst.
Developmental Cell
Weaver, S., Dube, S., Mir, A., Qin, J., Sun, G.,Ramakrishnan,R., Jones, R.C., Livak K.J. April 1, 2010. Taking qPCR to a Higher Level: Analysis of CNV Reveals the Power ofHigh Throughput qPCR to Enhance Quantitative Resolution.
Methods
.
Hosokawa, K., Arai, F., Yoshihara,H., Iwasaki,H., Hembree, M., Yin, T., Nakamura,Y., Gomei,Y., Takubo, K., Shiama, H., Matsuoka,S., Li,L.,Suda, T. March 5, 2010. Cadherin-based adhesion is a potential target forniche manipulationto protect hematopoietic stem cells in *****bone marrow.
Cell Stem Cell
Wilding, P., Verpoorte, S., Northrup, M.A., Yager, P.,Quake,S., and Landers, J. February 18, 2010. Microtechnology in Clinical Laboratory: Will it solve analyticalproblems.
Clinical Chemistry
Ralston,A., Cox, B.J., Nishioka, N., Sasaki, H., Chea,E.,Rugg-Gunn, P., Guo, G., Robson, P., Draper, J.S., andRossant,J. February 1, 2010. Gata3 regulatestrophoblast development downstream ofTead4 and in parallel toCdx2.
Development
Elizarov, A.M., van Dam, R.M., Shin, Y.S., Kolb, H.C.,Padgett,H.C., Stout, D., Shu, J., Huang, J., Daridon A., &Heath,J.R. February, 1, 2010. Design and Optimization of Coin-Shaped Microreactor Chips for PETRadiopharmaceutical Synthesis.
Journal of NuclearMedicine
Van Baarsen, L.G., Wijbrandts, C.A., Rustenburg, F.,Cantaert,T., van der Pouw Kraan, T.C., Baeten, D.L., Dijkmans,B.A., Tak,P.P., and Verweij, C.L. January 22, 2010. Regulation of IFNresponse gene activity during infliximabtreatment in rheumatoidarthritis is associated with clinicalresponse to treatment.
Arthritis Research &Therapy
Wang, J., Ramakrishnan, R., Tang, Z., Fan, W., Kluge,A.,Dowlati , A., Jones, R.C., Ma, P.C. Jan 19, 2010. Quantifying EGFR Alterations in the Lung Cancer Genome withNanofluidic Digital PCR Arrays.
Clinical Chemistry
Kimberlin, C.R., Bornholdt, Z.A., Li, S., Woods Jr,V.L.,MacRae, I.J., and Saphire, E.O. Jan 10, 2010. Ebolavirus VP35uses a bimodal strategy to bind dsRNA forinnate immunesuppression.
PNAS
2009
Kato, M., Kawaguchi, T., Ishikawa, S., Umeda, T., Nakamichi,R.,Shapero, M.H., Jones, K.W., Nakamura, Y., Aburatani, H.,andTsunoda, T. 2009 Dec 23. Population-genetic nature of copy number variations in the humangenome.
Human Molecular Genetics
.
Wang, J., Lin, M., Crenshaw, A., Hutchinson, A., Hicks,B.,Yeager, M., Berndt, S., Huang, W.,Hayes, R.B., Chanock,S.J.,Jones, R.C., and Ramakrishnan, R. 2009 Nov 28. High-throughputsingle nucleotide polymorphism genotypingusing nanofluidic DynamicArrays.
BMC Genomics
.
Bujold, M.,Gopalakrishnan, A., Nally, E., King-Jones, K. 2009 Nov 23. Thenuclear receptor DHR96 acts as a sentinel for low cholesterolconcentrations in Drosophila.
Mol Cell Biol.
Jones, D., Yao, H., Romans, A., Dando, C., Pierce,S.,Borthakur,G., Hamilton, A., Bueso-Ramos, C., Ravandi,F.,Garcia-Manero, G., Kantarjian, H. 2009 Nov 11. Modeling interactionsbetween leukemia-specificchromosomal changes, somatic mutations,and gene expressionpatterns during progression of core-bindingfactor leukemias.
Wiley InterScience
.
Yuan, P., Han, J., Guo, G., Orlov, Y.L., Huss, M., Loh, Y.,Yaw,L., Robson, P., Lim, B., and Ng, H. 2009 Nov 01. Eset partners with Oct4 to restrict extraembryonic trophoblastlineage potential in embryonic stem cells.
Genes Dev.
Sikora, A., Zimmermann, B.G., Rusterholz, C., Birri, D.,Kolla,V., Lapaire, O., Hoesli, I., Kiefer, V., Jackson, L., andHahn, S.2009. Detection of Increased Amounts of Cell-Free Fetal DNA with ShortPCR Amplicons.
Clinical Chemistry
.
Lee, D.W., Rajagopalan, S., Siddiq, A., Gwiazda, R., Yang,L.,Beal, M.F., Ratan, R.R. and Andersen, J.K. 2009 Oct 16. Inhibition of Prolyl Hydroxylase Protects against1-Methyl-4-phenyl-,3,6-tetrahydropyridine-inducedNeurotoxicity.
The Journal of Biological Chemistry.
Corbisier, P., Bhat, S., Partis, L., Rui Dan Xie, V.,Emslie,K.R., 2009 Oct 9. Absolutequantification of genetically modified MON810 maize (Zea mays L.)by digital polymerase chain reaction.
Anal BioanalChem.
[Epub ahead of print]
Seeb, J.E., Pascal, C.E., Ramakrishnan, R., Seeb, L.W.2009.SNPgenotyping by the 5'-nuclease reaction:advances in high-throughputgenotyping with nonmodel organisms.
Methods Mol Biol.
[Epubahead of print]
Helzer, K.T., Barnes, H.E., Day, L., Harvey, J., Billings,P.R.,and Forsyth A. 2009 Sep 29. Circulating Tumor Cells Are Transcriptionally Similar to thePrimary Tumor in a Murine Prostate Model.
CancerResearch
. [Epub ahead of print]
Byrne, J.A., Nguyen, H.N., Reijo Pera, R.A. 2009 Sept23.Enhanced Generation of Induced Pluripotent Stem Cells from aSubpopulation of Human Fibroblasts.
PLoS ONE
.
J. P. C. da Cunhaa, P. A. F. Galantea, J. E. de Souzaa, R. F.etal . 2009 Sept 15. Bioinformaticsconstruction of the human cellsurfaceome.
PNAS
.
Nicholas, C.R., Haston, K.M., Grewall, A.K., Longacre, T.A.andReijo Pera, R.A. 2009 Aug 20. Transplantation directs oocyte maturation from embryonic stem cellsand provides a therapeutic strategy for female infertility.
Human Molecular Genetics
.
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Pushkarev, D., Neff,N.F., Quake, S.R. 2009 Aug 10. Single-molecule sequencing of anindividual human genome.
Nat Biotechnol.
[Epub ahead ofprint]
[Editor's Note: The SlingShot™ Kit from Fluidigm was usedinthis project to quantitate samples for sequencing]
van Erp, N.P., Eechoutem K., van der Veldt, A.A., et.al.2009Aug 10. PharmacogeneticPathway Analysis for Determinationof Sunitinib-Induced Toxicity.
J Clin Oncol
. [Epub aheadof print]
Leong, D. E., Hahn-Windgassen, A., Foygel, K., Jun, S.,Behr,B., Yao, M.W.M. 2009. Morpholino-mediated gene knockdown in the early mouseembryo.
Nat Prot
[Protocols Network]
View Protocol
Orina, J.N., Calcagno, A.M., Wu, C.P., et.al. 2009 July7.Evaluation of currentmethods used to analyze theexpression profiles of ATP-bindingcassette transporters yields animproved drug-discoverydatabase.
Mol Cancer Ther.
8(7):2057-66
Sato, T., Onai, N., Yoshihara, H., Arai, F., Suda, T.,Ohteki,T. 2009 June. Interferon regulatoryfactor-2 protects quiescenthematopoietic stem cells from type Iinterferon-dependentexhaustion.
Nat Med.
15(6):696-700.
Haston, K.M., Tung, J.Y., Reijo Pera, R.A. 2009 May 21.Dazl functions inmaintenance of pluripotency and genetic and epigenetic programs ofdifferentiation in mouse primordial germ cells in vivo and invitro.
PLoS ONE
. 4(5):e5654
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Article
Fan, H.C., Blumenfeld, Y.J., El-Sayed, Y.Y., Chueh, J.,Quake,S.R. 2009 May. Microfluidic digital PCR enables rapidprenataldiagnosis of fetal aneuploidy.
Am J ObstetGynecol.
200(5):543.e1-7
Berndt, J.D., Biechele, T.L., Moon, R.T., Major, M.B. 2009May12. Integrative analysisof genome-wide RNA interference screens.
Sci Signal.2(70):pt4.
Weinstein, J.A., Jiang, N., White, R.A. 3rd, Fisher,D.S.,Quake, S.R. 2009 May 8. High-throughputsequencing of the zebrafish antibodyrepertoire.
Science.
324(5928):807-10.
[Editor's Note: The SlingShot™ Kitfrom Fluidigm was used inthis project to quantitate samples forsequencing]
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Article
Bhat, S., Herrmann, J., Armishaw, P., Corbisier, P.,Emslie,K.R. 2009 May. Single moleculedetection in nanofluidic digital arrayenables accurate measurementof DNA copy number.
AnalBioanal Chem
. 394(2):457-67.
Diehn, M., Cho, R.W., Lobo, N.A., et al. 2009 April 9.Association ofreactive oxygen species levels and radioresistance in cancer stemcells.
Nature.
9; 458: 780-783.
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Article
Lee, J.E., Fusco, M.L., Saphire, E.O. 2009 Apr 2. Anefficient platform for screening expression andcrystallization ofglycoproteins produced in human cells.
Nat Protoc.4(4):592-604
.
Farber, C.R., Aten, J.A., Farber, E.A., et al. 2009 Mar31.Genetic dissection ofa major mouse obesity QTL (Carfhg2):Integration of gene expressionand causality modeling.
Physiol Genomics.
Garrett,T.P., Burgess, A.W., Gan, H.K., et al. 2009 Mar31.Antibodiesspecifically targeting a locally misfolded region of tumorassociated EGFR.
PNAS. 106(13):5082-7
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White, R.A. 3rd, Blainey, P.C., Fan, H.C., Quake, S.R. 2009Mar19. Digital PCR providessensitive and absolute calibration for high throughput sequencing.BMC Genomics. 10(1):116.
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Yung, T.K., Chan, K.C., Mok, T.S., Tong, J., To, K.F., Lo,Y.M.2009 Mar 15. Single-MoleculeDetection of Epidermal GrowthFactor Receptor Mutations in Plasma byMicrofluidics Digital PCR inNon-Small Cell Lung CancerPatients.
Clin Cancer Res
.15(6):2076-2084.
Lo, Y.M.D. 2009 Jan. Noninvasive prenataldetection of fetal chromosomalaneuploidies by maternal plasmanucleic acid analysis: a review ofthe current state of the art.
BJOG
. 116:152-157.
[Editor's Note:"..automated platforms for conducting digitalPCR." referenced inthis paper (p156) is the Fluidigm BioMark RealTime System andFluidigm 12.765 Digital Arrays"]
2008
Foygel, K., Choi, B., Jun, S., et al., 2008 Dec 31. ANovel and Critical Role for Oct4 as a Regulator of theMaternal-Embryonic Transition.
PLoS ONE.
3(12): e4109.
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Zimmermann, B.G., Grill, S., Holzgreve, W., Zhong,X.Y.,Jackson, L.G., Hahn, S., 2008 Dec. Digital PCR: apowerful new tool for noninvasive prenataldiagnosis?
PrenatDiagn.
28(12):1087-93.
Golden, T.R., Hubbard, A., Dando, C., Herren, M.A., Melov,S.,2008 Dec. Age-related behaviorshave distinct transcriptionalprofiles in Caenorhabditiselegans.
Aging Cell.
7(6):850-65.
Major, M.B., Roberts, B.S., Berndt, J.D., et al., 2008 Nov11.New regulators ofWnt/beta-catenin signaling revealed byintegrative molecularscreening.
Sci Signal
.1(45):ra12.
Yao, Y., Higgs, B.W.,Morehouse, C., et al., 2008 Nov 5. Developmentof potential pharmacodynamic and diagnostic markers for anti-IFN-amonoclonal antibody trials in systemic lupus erythematosus.
Human Genomics and Proteomics
, 2009: 16 pages
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Kuchenbauer, F., Morin, R.D., Argiropoulos, B., et al.,2008Nov, In-depthcharacterization of the microRNA transcriptome in a leukemiaprogression model.
Genome Res
. 18(11):1787-97.
Chang, C.P., Nagel, D., Zaghloul, M., Nov-Dec 2008, Go with the (micro) flow.
IEEE Potentials
.27(6):17-25.
Dube, S., Mir, A., Jones, R.C., Ramakrishnan, R., Sun, G.,2008Oct 27. Computation of Maximal Resolutionof Copy Number Variationon a Nanofluidic Device using Digital PCR.arXiv:0809.1460v2[q-bio.GN]
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Fan, H.C., Blumenfeld, Y.J., Chitkara, U., Hudgins, L.,andQuake, S.R. 2008 Oct 21. Noninvasive diagnosisof fetal aneuploidy by shotgunsequencing DNA from maternal blood.
PNAS.
105(42):16266-71.
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Jedrusik, A., Parfitt, D.E., Guo, G., et. al., 2008 Oct1.Role of Cdx2 and cellpolarity in cell allocation andspecification of trophectoderm andinner cell mass in the mouseembryo.
Genes Dev
.22(19):2692-706
Qin, J., Jones, R.C., Ramakrishnan, R. 2008 Oct. Studying copy numbervariations using a nanofluidicplatform.
Nucleic AcidsResearch.
36(18):e116.
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Weisenberger, D.J., Trinh, B.N., Campan, M., et al. 2008Aug.DNA methylationanalysis by digital bisulfite genomicsequencing and digitalMethyLight.
Nucleic Acids Research.
36(14):4689-98.
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Lun, F.M., Chiu, R.W., Chan, K.C., Leung, T.Y., Lau, T.K.,Lo,Y.M. 2008 Aug 14. Microfluidics DigitalPCR Reveals a Higher than ExpectedFraction of Fetal DNA in MaternalPlasma.
ClinicalChemistry
. 54(10).
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Dube, S., Qin, J., Ramakrishnan, R. 2008 Aug 6. Mathematical Analysisof Copy Number Variation in a DNASample Using Digital PCR on aNanofluidic Device.
PLoSONE.
3(8): e2876.
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Yao, Y., Richman, L., Morehouse, C., et al. 2008 Jul16.Type I Interferon:Potential Therapeutic Target forPsoriasis?
PLoSONE
.3(7):e2737.
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Oehler, V.G., Qin, J., Ramakrishnan, R., et. al. 2008 Jul10.Absolute quantitativedetection of ABL tyrosine kinasedomain point mutations in chronicmyeloid leukemia using a novelnanofluidic platform andmutation-specific PCR.
Leukemia.
Lee, J.E., Fusco, M.L., Hessell, A.J., Oswald, W.B.,Burton,D.R., Saphire, E.O. 2008 Jul 10. Structure of theEbola virus glycoprotein bound to anantibody from a humansurvivor.
Nature.
454(7201):177-82.
Iino, H., Naitow, H., Nakamura, Y., et. al. 2008 Jun 1.Crystallizationscreening test for the whole-cell project on Thermus thermophilusHB8.
Acta Crystallogr Sect F Struct Biol Cryst Commun.
64(Pt 6):487-91.
Ishikawa, S., Umeda, T. 2008 May 31. Current status of CNV research and related methods.
ClinicalGenome Research (Japan).
229(9).
Spurgeon, S.L., Jones, R. C., Ramakrishnan, R. 2008 Feb27.High throughput geneexpression measurement with real timePCR in a microfluidic dynamicarray.
PLoSONE
.3(2):e1662.
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Heras, B., Kurz, M., Jarrott, R., et al. 2008 Feb 15. Staphylococcus aureus DsbA does not have a destabilizing disulfide. A new paradigm for bacterial oxidative folding
.
J Biol Chem.
15;283(7):4261-71
Kwon, H.J., Lagace, T.A., McNutt, M.C., Horton,J.D.,Deisenhofer, J. 2008 Feb 12. Molecular basis forLDL receptor recognition by PCSK9.
Proc Natl Acad Sci USA.
105(6):1820-5.
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2007
Habicht, C., Templin, W.D., Willette, T.M., Fair, L.F.,Raborn,S.W., and Seeb, L.W. 2007 Dec. Post-seasonstock composition analysis of Upper Cook Inletsockeye salmonharvest, 2005-2007.
Alaska Department of Fishand Game, FisheryManuscript No.07-07, Anchorage
.
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Sindelka, R., Jonak, J., Hands, R., Bustin, S.A., andKubista,M. 2007 Nov 26. Intracellularexpression profiles measured by real-timePCR tomography in theXenopus laevis oocyte.
Nucleic AcidsResearch.
36(2):387-392.
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Heras, B., Kurz, M., Jarrott, R., et al. 2007 Nov 1. Expression and crystallization of DsbA from Staphylococcus aureus.
Acta Crystallogr Sect F Struct Biol Cryst Commun
. 63(Pt 11):953-6.
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Yasui, N., Nogi, T., Kitao, T., Nakano, Y., Hattori, M.,andTakagi, J. 2007 Jun 12. Structure of areceptor-binding fragment of reelin andmutational analysis reveal arecognition mechanism similar toendocytic receptors.
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Latham, C.F., Hu, S.H., Gee, C.L. et al. 2007 Jun 1. Crystallization and preliminary X-ray diffraction of the Munc18c-syntaxin4 1-29 complex.
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2006
Ottesen, E.A., Hong, J.W., Quake, S.R., and Leadbetter,J.R.2006 Dec 1. Microfluidic digitalPCR enables multigene analysisof individual environmental bacteria.
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Warren, L., Bryder, D., Weissman, I.L., and Quake, S.R. 2006Nov21. Transcription factorprofiling in individualhematopoietic progenitors by digital RT-PCR.
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English, C.M., Adkins, M.W., Carson, J.J., Churchill, M.E.,andTyler J.K. 2006 Nov 3. Structural basis forthe histone chaperone activity ofAsf1.
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Stevens, J., Blixt, O., Tumpey, T.M., Taubenberger,J.K.,Paulson, J.C., and Wilson, I.A. 2006 Apr 21. Structure andreceptor specificity of the hemagglutininfrom an H5N1 influenzavirus.
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2005
Lee C.C., Sui, G., Elizarov, A. et al. 2005 Dec 16. Multistep synthesis of a radiolabeled imaging probe usingintegrated microfluidics.
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2004
Hansen, C.L., Sommer, M.O., and Quake S.R. 2004 Oct 5.Systematicinvestigation of protein phase behavior with a microfluidicformulator.
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Xiao, T., Takagi, J., Coller, B.S., Wang, J.H., andSpringerT.A. 2004 Nov 4. Structural basis forallostery in integrins and binding tofibrinogen-mimetictherapeutics.
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2003
Liu, J., Hansen, C., and Quake, S.R. 2003 Sep 15. Solvingthe 'world-to-chip' interface problem with amicrofluidic matrix.
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Wheeler, A.R., Throndset, W.R., Whelan, R.J., et al. 2003Jul15. Microfluidic devicefor single-cell analysis.
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2002
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2001Fluidigm(富鲁达)高通量基因分析系统相关应用技术文章
Chou, H.P., Unger, M.A., and Quake, S.R. 2001 Dec. A microfabricated rotary pump.
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2000Fluidigm(富鲁达)高通量基因分析系统相关应用技术文章
Quake, S.R. and Scherer, A. 2000 Nov 24. Frommicro- tonanofabrication with soft materials.
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Unger, M.A., Chou, H.P., Thorsen, T., Scherer, A., andQuake,S.R. 2000 Apr 7. Monolithicmicrofabricated valves and pumps by multilayersoft lithography.
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1999Fluidigm(富鲁达)高通量基因分析系统相关应用技术文章
Fu, A.Y., Spence, C., Scherer, A., Arnold, F.H., and Quake,S.R.1999 Nov. Amicrofabricatedfluorescence-activated cell sorter.
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Chou, H.P., Spence, C., Scherer, A., and Quake, S. 1999 Jan5.A microfabricateddevice for sizing and sorting DNAmolecules.
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Fluidigm(富鲁达)高通量基因分析系统相关应用技术文章
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