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| 试剂厂家LUXCEL提供独有的时间分辨荧光探针技术,令研究者可在 BMG**TRF荧光酶标仪上用细胞或分离的线粒体进行简单的,高通量的和实时的胞外氧消秏量(ecOCR),胞内氧消秏量(icOCR)和胞外酸化率(ECA)等代谢指标检测。 | |
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综合不同LUXCEL试剂,研究者可在同一样本中进行多个细胞代谢,线粒体功能与毒性指标检测(e.g. ORC,ECA和ATP) 。 |
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·MitoXpress®Intra-检测胞内氧消秏 |
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·pH-XtraTM-检测胞外酸化率 |
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The Enzymatic Activity of Apoptosis Inducing Factor Supports Energy Metabolism Benefitting the Growth and Invasiveness of Advanced Prostate Cancer Cells Lewis EM, Wilkinson AS, Jackson JS, Mehra R, Varambally S, Chinnaiyan AM, Wilkinson JC., J Biol Chem. (2012 Nov) . |
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Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways Farabegoli F, Vettraino M, Manerba M, Fiume L, Roberti M, Di Stefano G., Eur J Pharm Sci. (2012 Nov); 47(4):729-38 |
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Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria Porceddu M, Buron N, Roussel C, Labbe G, Fromenty B, Borgne-Sanchez A. Toxicol Sci. (2012 Oct);129(2):332-45 |
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Overexpression of Pyruvate Dehydrogenase Kinase 1 and Lactate Dehydrogenase A in Nerve Cells Confers Resistance to Amyloid β and Other Toxins by Decreasing Mitochondrial Respiration and Reactive Oxygen Species Production Newington JT, Rappon T, Albers S, Wong DY, Rylett RJ, Cumming RC., J Biol. (2012 Oct); 287(44):37245-58 |
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Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply Mottillo EP, Bloch AE, Leff T, Granneman JG. J Biol Chem. (2012 Jul); 287(30):25038-48 |
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Geranylgeraniol oxidase activity involved in oxidative formation of geranylgeranoic acid in human hepatoma cells Mitake M, Shidoji Y., Biomed Res. (2012 Feb);33(1):15-24 |
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Nuclear Expression of a Mitochondrial DNA Gene: Mitochondrial Targeting of Allotopically Expressed Mutant ATP6 in Transgenic Mice Dunn, Carl A. Pinker, J Biomed Biotechnol. (2012) |
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Modular microfluidic system as a model of cystic fibrosis airways Skolimowski M, Nielsen MW, Abeille F, Skafte-Pedersen P, Sabourin D, Fercher A, Papkovsky D, Molin S, Taboryski R, Sternberg C, Dufva M, Geschke O, Emnéus J., Biomicrofluidics, (2012), 6, 034109 |
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In vitro approach to predict post-translational phosphorylation response to mixtures Jonathan Boyd, Julie A. Vrana, Holly N. Williams, Tox (2012) |
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A high-throughput dual parameter assay for assessing drug-induced mitochondrial dysfunction provides additional predictivity over two established mitochondrial … J Hynes, S Nadanaciva, R Swiss, C Carey, S Kirwan… – Toxicology in Vitro, 2012 |
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