Daidzein, >99%

Storage:  Store at or below -20 ºC. Solubility:  Soluble in DMSO; very poorly soluble in other solvents.  Disposal:  A

 

• Negative control for genistein.  Akiyama, T., et al.  "Genistein, a specific inhibitor of tyrosine-specific protein kinases."  J. Biol. Chem. 262:  5592-5595 (1987).  Wijetunge, S. et al. Tyrosine kinase inhibitors block calcium channel currents in vascular smooth muscle cells."  Biochem. Biophys. Res. Comm. 189:  1620-1623 (1992).

• Daidzein is also a cytostatic agent capable of arresting the cell cycle at G1.  Higashi, K. and Ogawara, H.  "Daidzein inhibits insulin- or insulin-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells."  Biochim Biophys Acta. 1221:  29-35 (1994).

• Weak inhibitor of hamster mitochondrial alcohol dehydrogenase.  Keung, W.M., Klyosov, A.A., and Vallee, B.L.  "Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters."  Proc. Natl. Acad. Sci. USA 94:  1675-1679 (1997).

• Isoflavone derivative found in soy-based food products.  Wang, H. and Murphy, P.A.  "Isoflavone content in commercial soybean foods."  J. Agric. Food Chem. 42:  1666-1673 (1994).

• See also these related products:

  A-6900   6"-O-Acetyldaidzin

  D-7878   Daidzin

  D-9200   (R,S)-Dihydrodaidzein

  E-5880   (R,S)-Equol

  M-6730   6"-O-Malonyldaidzin

• Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.

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