7-Ethyl-10-hydroxycamptothecin (SN-38; NK012);7-乙基-10-羟基喜树碱 (SN-38);CAS:86639-52-3
Formula:C22H20N2O5
Molecular Weight：392.40
Appearance：Light yellow crystalline powder
Purity：98+%
SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively.SN-38 (NK012) 是拓扑异构酶 I (Topoisomerase I) 抑制剂伊立替康的活性代谢产物