Nintedanib Ethanesulfonate Salt; Nintedanib(ethanesulfonic acid); BIBF 1120 esylate; Nintedanib esylate;尼达尼布乙磺酸盐;CAS:656247-18-6.
Formula:C31H33N5O4.C2H6O3S
Molecular Weight:649.76
Appearance:Yellow solid
Purity:98+%
Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.Nintedanib esylate (BIBF 1120 esylate) 是一种有效的 VEGFR1/2/3,FGFR1/2/3 和 PDGFRα/β 三重抑制剂,IC50 值分别为 34 nM/13 nM/13 nM,69 nM/37 nM/108 nM 和 59 nM/65 nM 仅用于工业应用或科学研究,不可用于人类或动物的临床诊断,非药用