Vandetanib (ZD6474);凡德他尼;CAS:443913-73-3.
Formula:C22H24BrFN4O2
Molecular Weight:475.35
Appearance:White Powder
Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM).Vandetanib (D6474)