Brefeldin A;布雷菲德菌素A;CAS:20350-15-6.
Formula:C16H24O4
Molecular Weight:280.36
Appearance:Off-white powder
Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus.Brefeldin A is also an autophagy and mitophagy inhibitor.Brefeldin A is a CRISPR/Cas9 activator.Brefeldin A inhibits HSV-1 and has anti-cancer activity.