Mitoxantrone dihydrochloride；70476-82-3 CL2210A 上海佰世凯化学科技有限公司

Mitoxantrone dihydrochloride；70476-82-3

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产品名称：Mitoxantrone dihydrochloride；70476-82-3
产品型号：CL2210A
产品展商：Chembest
产品文档：无相关文档

简单介绍

Mitoxantrone dihydrochloride；盐酸米托蒽醌；70476-82-3 Formula：C22H30Cl2N4O6

产品描述

Mitoxantrone dihydrochloride；盐酸米托蒽醌；70476-82-3 Formula：C22H30Cl2N4O6

Formula:C22H29ClN4O6.2HCl

Molecular Weight：517.4

Appearance：Dark blue powder

Purity：98+%

Mitoxantrone is an anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5.3 μM), thus inhibiting cell proliferation. It also inhibits HIV-1 integrase (IC50 = 3.8 μM). Mitoxantrone is exported from cells in an ATP- and glutathione-dependent manner by multidrug resistance protein-1.4 Formulations containing mitoxantrone have been used in the treatment of cancer and multiple sclerosis.

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Mitoxantrone dihydrochloride；70476-82-3