Belinostat;866323-14-0;Belinostat Formula: C15H14N2O4S
Formula:C15H14N2O4S
Molecular Weight:318.35
Appearance:Off-white crystalline powder
Purity:98+%
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.