Cobimetinib;考比替尼;934660-93-2
Formula:C21H21F3IN3O2
Molecular Weight:531.31
Appearance:Off-white solid powder
Purity:98+%
Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, and showing no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.