WP1066;WP1066;857064-38-1
Formula:C17H14BrN3O
Molecular Weight:356.22
Appearance:White to off-white crystalline powder
Purity:98+%
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. WP1066 induces apoptosis. Phase 1.