Topotecan hydrochloride;盐酸拓扑替康/盐酸托泊替康;119413-54-6
Formula:C23H23N3O5.HCl
Molecular Weight:457.91
Appearance:Off-white to yellow powder
Purity:98+%
Topotecan HCl is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. Topotecan HCl induces autophagy and apoptosis.