Nilotinib HCL monohydrate;尼罗替尼盐酸一水合物;923288-90-8
Formula:C28H25ClF3N7O2
Molecular Weight:584.00
Appearance:White to off-white powder
Purity:98+%
Nilotinib (AMN-107, Tasigna) hydrochloride monohydrate is a selective and orally bioavailable inhibitor of Bcr-Abl with IC50 < 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.