Doxorubicin hydrochloride;盐酸多柔比星,盐酸阿霉素;25316-40-9
Formula:C27H29NO11.HCl
Molecular Weight: 579.98
Appearance:Orange red powder
Purity:98+%
Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy