Licofelone;利克飞龙;156897-06-2
Formula:C23H22ClNO2
Molecular Weight:379.88
Appearance:Off-white powder
Purity:98+%
Licofelone (ML3000, Compound 3e) is a dual inhibitor of COX and 5-lipoxygenase (5-LOX) with IC50 of 0.21 μM and 0.18 μM, respectively. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins. Licofelone is considered as a treatment for osteoarthritis.