Tobramycin Base;32986-56-4 CL2155 上海佰世凯化学科技有限公司

Tobramycin Base;32986-56-4

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产品名称：Tobramycin Base;32986-56-4
产品型号：CL2155
产品展商：Chembest
产品文档：无相关文档

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Tobramycin Base;妥布霉素;32986-56-4

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Tobramycin Base;妥布霉素;32986-56-4 Formula:C18H37N5O9 Tobramycin is an effective antibiotic commonly used in the management and treatment of various systemic and ocular infections. As an aminoglycoside antibiotic, tobramycin is active against aerobic gram-negative bacteria, including Pseudomonas aeruginosa. Tobramycin binds to the 16s ribosomal RNA component of the bacterial 30s ribosomal unit, inhibiting the initiation step of translation. By binding to the A-site, tobramycin induces mistranslation and causes transfer RNA to misread the codon, thus causing incorrect delivery of aminoacyl units. Incorrectly synthesized proteins build up inside the cell, disrupting the cell membrane and various cellular processes; this mechanism of action designates tobramycin as a bactericidal agent.

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Tobramycin Base;32986-56-4