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Zalcitabine;7481-89-2

Zalcitabine;7481-89-2
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  • 产品名称:Zalcitabine;7481-89-2
  • 产品型号:CL2159
  • 产品展商:Chembest
  • 产品文档:无相关文档
简单介绍
Zalcitabine;扎西他滨;7481-89-2
产品描述
Zalcitabine;扎西他滨;7481-89-2 Formula:C9H13N3O3 Zalcitabine (trade name Hivid) is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI). It is an antiviral pyrimidine nucleoside analogue effective against HIV replication. 2′,3′-Dideoxycytidine, when activated to its triphosphate, is incorporated into DNA by HIV-1 RT (HIV-1 reverse transcriptase), causing DNA chain termination and viral replication. Zalcitabine was the third antiretroviral to be approved by the Food and Drug Administration (FDA) for the treatment of HIV/AIDS. It is used as part of a combination regimen. Zalcitabine appears less potent than some other nucleoside RTIs, has an inconvenient three-times daily frequency and is associated with serious adverse events.
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