产品名称：Monoclonal Antibody to Human C6

产品介绍
品名	Monoclonal Antibody to Human C6
货号	A219
规格	100 µL
同种型	IgG1k
蛋白质浓度	> 1.0 mg/mL
纯度	≥ 95% by SDS PAGE
缓冲液	Borate Buffered Saline (pH 8.4 ± 0.2)
物种交叉反应	Human, baboon, Cynomolgus macaque, Rhesus macaque.
储存	≤ 30 Days 2-8˚C  > 30 Days ≤ –20˚C
使用说明	For Research Use Only. Not for use in diagnostic procedures
产品描述	A murine monoclonal antibody to an epitope on C6 protein. This monoclonal antibody was raised against purified human C. It is specific for an antigen expressed both on the native C6 molecule as well as on C6 in the MAC. It will not inhibit lysis of EA and will bind to MAC bound to a membrane. Quidel's C6 monoclonal antibody has been used in a variety of experimental techniques including EIA, Western Blot, and Immunohistochemistry
特异性	The specificity of the monoclonal antibody for Complement protein, C6 was established by ELISA and radioimmunoassay (RIA). The antibody was also shown to bind isolated SC5b-9 and complement-lysed rabbit erythrocyte ghosts by indirect immunofluorescence.
应用
参考资料	1、Thorgersen, EB. et al. Inhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood. Infect Immun. 77(2):725-732 (2002).  2、Plested, JS. and Granoff, DM. Vaccine-induced opsonophagocytic immunity to Neisseria meningitidis group B. Clin Vaccine Immunol. 15(5):799- 804 (2008).  3、Ragupathi, G. et al. Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity . J Immunol. 174(9):5706-5712 (2005).