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  • 入驻时间: 2012-04-17
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产品详情
  • 产品名称:PDX1 (p11) Antibody

  • 产品型号:abx032067
  • 产品厂商:Abbexa
  • 产品价格:190
  • 折扣价格:0
  • 产品文档:
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简单介绍:
PDX1 (p11) Antibody
详情介绍:
PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this protein are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Target PDX1 (p11)
Reactivity Human
Host Rabbit
Clonality Polyclonal
Tested Applications DB
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Immunogen Human PDX1 (phospho-Thr11).
Purification Purified Rabbit Polyclonal Antibody.
Isotype IgG
Conjugation Unconjugated
Specificity This PDX1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T11 of human PDX1.
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot P52945
Buffer PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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