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第12年
- 入驻时间： 2012-04-17
- 联系人：客户经理
- 电话：400-968-7988
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- Email：fuwu@bioleaf.com
产品详情
简单介绍：
PDX1 (p11) Antibody
详情介绍：
PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this protein are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
| Target | PDX1 (p11) |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Tested Applications | DB |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen | Human PDX1 (phospho-Thr11). |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Specificity | This PDX1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T11 of human PDX1. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot | P52945 |
| Buffer | PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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